詹其琛

时间:2024-03-20浏览:19

姓名:詹其琛

职称:副教授、硕士生导师

E-mailzhanqichen@njucm.edu.cn

主要研究方向:药物制剂与产品研发,聚焦中药功效物质到颗粒效应的范式转变及其在疾病治疗中的应用研究


个人简介

博士,硕士生导师。担任中药制药过程控制与智能制造技术全国重点实验室科研管理中心主任,江苏省药理学会中药药理专业委员会秘书。入选江苏省青年科技人才托举工程、江苏省科技副总。主持国家自然科学基金青年项目等纵向课题3项、横向课题2项;以第一作者及通讯作者在Journal of Controlled Release, Small, Chemical Engineering Journal, Advanced Healthcare Materials等期刊发表研究论文21篇,教学论文2篇;公开发明专利7项,已授权1项。


承担的主要科研项目

1. 国家自然科学基金青年基金,2022/01-2024/1230万,主持,结题;

2. 江苏省青年科技人才托举工程,2025/01-2026/122万,主持,在研;

3. 南京中医药大学自然科学基金,2022/01-2024/1224万,主持,结题;

4. 横向课题,止痒方院内制剂研发,2024/08-2026/1245万,主持,在研;

5. 横向课题,基于推理模型的专病诊疗与药物筛选,2026/02-2029/02200万,主持,在研。


代表性论文

1.Cheng Chen, Qichen Zhan* and Peng Cao*, et al. A thermoresponsive magnetic nanocarrier with the DNA-mimetic base pairing-guided controlled release of methotrexate in the treatment of rheumatoid arthritis, Journal of Controlled Release, 2025, 384, 113952. (共同通讯,中科院一区,IF=11.5)

2.Feng Gao, Qichen Zhan* and Peng Cao*, et al. Adenosine triphosphate-triggered aggregable DNA micelles for triple enhanced photothermal therapy in the second near-infrared window, Journal of Controlled Release, 2025, 386, 114125. (共同通讯,中科院一区,IF=11.5)

3.Aimei Zhang, Qichen Zhan* and Peng Cao*, et al. Hydrogen sulfide delivery system based on salting-out effect for enhancing synergistic photothermal and photodynamic cancer therapies, Advanced Healthcare Materials, 2024, 13, 202400803. (共同通讯,中科院二区,IF=10.0)

4.Qichen Zhan,# Xianqing Shi,# Lin Zhou* and Shaohua Wei*, et al. Solvent mixing generating air bubbles as a template for polydopamine nanobowl fabrication: Underlying mechanism, nanomotor assembly and application in cancer treatment. Chemical Engineering Journal, 2021, 404, 126443. (共同第一作者,中科院一区,IF=15.1)

5.Qichen Zhan,# Xianqing Shi,# Lin Zhou* and Shaohua Wei*, et al. Drug-controlled release based on complementary base pairing rules for photodynamic-photothermal synergistic tumor treatment. Small, 2019, 15, 1803926. (共同第一作者,中科院一区,IF=13.3)