王月瑶

时间:2024-07-18浏览:365


姓名:王月瑶

职称:副教授

E-mailyueyao@njucm.edu.cn

主要研究方向:核酸化学


个人简介

       王月瑶,副教授、硕士生导师。主要从事非天然核酸的筛选、应用及其相关技术的研究。2022年博士毕业于南京大学现代工程与应用科学学院材料科学与工程专业。202212月正式入职南京中医药大学药学院。在Nature ChemistryJournal of the American Chemical Society等杂志发表论文7篇,授权发明专利1项,主持国家自然科学基金青年基金一项。


承担的主要科研项目

       国家自然科学基金青年科学基金项目(22307058),开发2’-氟阿拉伯糖核酸的自动化Sanger测序新方法,2024/01-2026/12,主持,30万元。


代表性论文10篇以内,需标注共同第一作者或共同通讯作者,论文格式需统一)

1.Yueyao Wang#, Yao Wang#, Dongfan Song, Xin Sun, Zhe Li*, Jia-Yu Chen and Hanyang Yu*.An RNA-cleaving Threose Nucleic Acid Enzyme Capable of Single Point Mutation Discrimination. Nat. Chem. 2022, 14(3):350.

2.Yueyao Wang, Jintao Yang, Xin Yuan, Jin Cao, Jiacui Xu, John C. Chaput, Zhe Li* and Hanyang Yu*. A Novel Small RNA-Cleaving Deoxyribozyme with a Short Binding Arm. Sci. Rep. 2019, 9(1):8224.

3.Yueyao Wang, Hanyang Yu. Characterization and Optimization of a Deoxyribozyme with a Short Left Binding Arm. Methods Mol. Biol. 2021, 2167, 79.

4.Yao Wang, Yueyao Wang, Dongfan Song, Xin Sun, Ze Zhang, Xintong Li, Zhe Li, and Hanyang Yu*. A Threose Nucleic Acid Enzyme with RNA Ligase Activity. J. Am. Chem. Soc. 2021, 143(21):8154.

5.Dongying Wei, Yueyao Wang, Dongfan Song, Ze Zhang, Juan Wang, Jia-Yu Chen, Zhe Li, and Hanyang Yu*. A Nucleic Acid Sequence That is Catalytically Active in Both RNA and TNA Backbones. ACS Synth. Biol. 2022, 11(11):3874.

6.Dongying Wei, Mingmei Gao, Jiajie Guo, Yueyao Wang, Xintong Li, Zhe Li*, Hanyang Yu*. DNA-catalysed Alternative RNA Splicing. Chem. Commun (Camb). 2022, 58(55):7698.

7.Mingmei Gao#, Dongying Wei#, Siqi Chen, Bohe Qin, Yueyao Wang, Zhe Li, Hanyang Yu*. Selection of RNA-Cleaving TNA Enzymes for Cellular Mg2+ Imaging. Chembiochem. 2023, 24(4):e202200651.