王晶晶

副教授

E-mail：wangjingjing@njucm.edu.cn

主要研究方向：

中药药剂

个人简介

1. Lu Li , Jia Liu , Xiuyan Shi , Chenman Yuan, Zhetong Jin, Xue Rui, Yi Chen, Lingchong Wang , Wei Li, Yugen Chen*, Jingjing Wang*. Inulin-armored hesperetin‑zinc nanodrugs for synergistic redox-immune modulation and barrier repair in ulcerative colitis. International Journal of Biological Macromolecules. 2026, 152088. （IF=8.65）

2.Xue Rui^#, Zhetong Jin^#, Lu Li, Jia Liu, Jiarong Mao, Xuejiao Leng, Hongzhi Qiao, Wei Li, Lingchong Wang, Yugen Chen,* and Jingjing Wang*. A platinum(IV)–crocetin nanoplatform with intracellular morphological transformation for enhanced colorectal cancer therapy, Journal of Chmeistry Materials B. 2025, 13 (22), 6483-6492. （IF=5.8）

3. Jiarong Mao^#, Zhetong Jin^#, Xue Rui, Lu Li, Chengchen Hou, Xuejiao Leng, Xiaolin Bi, Zhipeng Chen,* Yugen Chen,* and Jingjing Wang*. A Universal Cyclodextrin-Based Nanovaccine Platform Delivers Epitope Peptides for Enhanced Antitumor Immunity. Advanced Healthcare Materials. 2023:e2301099. （IF=10）

4. Ying Qian^#, Jiarong Mao^#, Xuejiao Leng, Ling Zhu, Xue Rui, Zhetong Jin, Houzhe Jiang, Heng Liu, Fengguang Zhang, Xiaolin Bi,Zhipeng Chen,and Jingjing Wang* Co-delivery of proanthocyanidin and mitoxantrone induce synergistic immunogenic cell death to potentiate cancer immunotherapy, Biomaterials Science, 2022, 10(16)：4549-4560. （IF=7.59）

5. Jingjing Wang, Xue Rui, Zhetong Jin, Xuejiao Leng, Zhipeng Chen*, Self-delivering supramolecular nanofiber based on peptide-rhein conjugate, Journal of nanomaterials, 2022, 6880220.

6. Jingjing Wang^#,Yin Qian^#,Liu Xu, Hu Zhang, Fanli Shi, Jiaxin Chen,Siqi Cui, Xiaoyan Chen, Dongwei Zhu, Rongfeng Hu, Zhipeng Chen*, Hyaluronic Acid Shelled, Peptide Drug Conjugate Cored Nanomedcine for the Treatment of Hepatocellular Carcinoma, Materials Science and Engineering: C Materials for Biological Applications. 2020, 117, 111261. (IF=7.328）

7. Chen Qian^#, Jingjing Wang^#, Ying Qian, Rongfeng Hu, Jiayu Zou, Chenqi Zhu, Yuan Zhu, Shuyang Qi, Xiaobin Jia, Li Wu, Weidong Li, and Zhipeng Chen*,Tumor-Cell-Surface Adherable Peptide-Drug Conjugate Prodrug Nanoparticles Inhibit Tumor Metastasis and Augment Treatment Efficacy，Nano Letters, 2020，20(6), 4153-4161. (IF=11.238）

8. Jingjing Wang*, Ying Qian, Chen Qian, Jingyuan Yao, Xiaolin Bi. Paclitaxel-loaded cyclodextrin-cored unimolecular micelles and their in vivo behavior, Reactive and Functional Polymers, 2020, 150, 104542.

9. Jingjing Wang, Ying Qian, Chen Qian, Fanli Shi, Jingyuan Yao, Xiaolin Bi, Zhipeng Chen*, A novel β-cyclodextrin-rhein conjugate for improving the water solubility and bioavailablity of rhein, Carbohydrate Research, 2020,490, 107958.

10. Rui Chen^#, Jingjing Wang^#, Chen Qian^#, Yujie Ji, Chenqi Zhu, Li Wu, Weidong Li, Xiaolin Bi, Yutong Wang, Gang Cao,* and Zhipeng Chen*, From Nanofibers to Nanorods: Nanostructure of Peptide-Drug Conjugates Regulated by Polypeptide-PEG Derivative and Enhanced Antitumor Effect, Advanced Functional Materials, 2019, 29(2):1806058.（IF=16.836）

科研项目

1.南京中医药大学中医肛肠优势专科临床一体化项目 2025/09-2026/12，主持，在研

2.企业联合科研项目基于肠道菌群调理小儿抽动秽语综合征的药材筛选，2024/03-2027/03，主持，10万，在研

3.国家自然科学基金青年项目，免疫复合纳米给药系统对微卫星稳定结直肠癌的协同治疗研究，2021/01-2023/12，主持，24万，结题

4.江苏省高等学校自然科学研究基金面上项目，DPPA-1/MITX/PC复合纳米药物对结直肠癌的免疫协同治疗研究，2020/12-2022/12，主持，5万，结题

5.南京中医药大学自然科学基金青年项目，免疫复合纳米给药系统对微卫星稳定结直肠癌的协同治疗研究，2021/01-2023/12，主持，24万，结题

6.南京中医药大学中医优势学科项目基于抗原多肽的纳米疫苗的构建及其对肿瘤的免疫治疗研究，2018/01-2021/12，主持，20万，结题

7.南京中医药大学药学院优势学科自然科学基金基于PDCs的纳米递药系统的构建及抗肿瘤研究2017/07-2019/06，主持，3万，结题

8.南京中医药大学自然科学基金富勒烯及环糊精偶联物纳米粒子的制备及抗肿瘤性能研究，2014/01-2015/12，主持，3万，结题

9.江苏省优秀青年基金，丹参多成分长效递释系统的构建及其应用研究，2019/07-2022/06，参与，50万元，结题

10.国家重点研发计划-中医药现代化研究，基于中药物料性质的(口服)剂型设计与制剂处方优化关键技术研究（子课题：多元微小丸及高载药量技术的中药释药系统设计关键技术研究），2018/12-2021/11，参与，151万，结题

11.国家自然科学基金面上项目，功能性自组装多肽药物结合物的设计及调控其自组装构建长效纳米药物的研究，2018/01-2021/12，参与，48万元，结题

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