谭仁祥

教授

发布者:花文婷发布时间:2024-07-18浏览次数:14228

1. Y. S. Wang+, W. Zheng+, N. Jiang+, Y. X. Jin+, Z. K. Meng, M. X. Sun, Y. L. Zong, T. Xu, J. P. Zhu*, R. X. Ren*. Alteration of the catalytic reaction trajectory of a vicinal oxygen chelate enzyme by directed evolution. Angew. Chem. Int. Ed.2022, doi:10.1002/anie.202201321.

2. X. M. Wu+, Q. Y. Guan+, Y. B. Han, X. C. Wang, W. Y. Zhuang, and R. X. Tan*. Regeneration of phytochemicals by structure-driven organization of microbial biosynthetic steps. Angew. Chem. Int. Ed.2022, 61, e202114919.

3. Y. B. Han+, W. Bai+, C. X. Ding, J. Liang, S.-H. Wu, and R. X. Tan*. Intertwined biosynthesis of skyrin and rugulosin A underlies the formation of cage-structured bisanthraquinones. J. Am. Chem. Soc. 2021, 143, 14218–14226.

4. F. W. Jiao+, Y. S. Wang+, X. T. You, W. Wei, Y. Chen, C. L. Yang, Z. K. Guo, B. Zhang, Y. Liang*, R. X. Tan*, R. H. Jiao* and H. M. Ge*. An NADPH-dependent ketoreductase catalyses the tetracyclic to pentacyclic skeletal rearrangement in chartreusin biosynthesis. Angew. Chem. Int. Ed.2021, 60, 1–8.

5. L. P. Lin+, D. Liu+, J. C. Qian, L. Wu, Q. Zhao, R. X. Tan*. Post-ingestion conversion of dietary indoles into anticancer agents. Nat. Sci. Rev. 2022, 9, nwab144.

6. G. Z. Dai, W. B. Han, Y. N. Mei, K. Xu, R. H. Jiao, H. M. Ge, R. X. Tan*. Pyridoxal-5’-phosphate-dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi. Proc. Natl. Acad. Sci. U.S.A.2020, 117, 1174–1180.

7. B. Zhang, K. B. Wang, W. Wang, X. Wang, F. Liu, J. P. Zhu, J. Shi, L. Y. Li, H. Han, K. Xu, H. Y. Qiao, X. Zhang, R. H. Jiao, K. N. Houk*, Y. Liang*, R. X. Tan*, H. M. Ge*. Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products. Nature2019, 568, 122–126.

8. X. M. Wu, R. X. Tan*. Interaction between gut microbiota and ethnomedicine constituents. Nat. Prod. Rep. 2019, 36, 788–809.

9. L. P. Lin, N. Jiang, H. M. Wu, Y. N. Mei, J. Yang, R. X. Tan*. Cytotoxic and antibacterial polyketide-indole hybrids synthesized from indole-3-carbinol by Daldinia eschscholzii. Acta Pharm. Sin. B 2019, 9, 369-380.

10. Z. Z. Zhou, H. J. Zhu, L. P. Lin, X. Zhang, H. M. Ge, R. H. Jiao, R. X. Tan*. Dalmanol biosyntheses require coupling of two separate polyketide gene clusters. Chem. Sci.2019, 10, 73–82.



南中医药学院南中医药学院学子南中医药学院研究生