麻彤辉

教授

E-mail：matonghui@njucm.edu.cn

主要研究方向：

水盐代谢机制及中药调控

个人简介

1.Li Y, Yang X, Bao T, Sun X, Li X, Zhu H, Zhang B*, Ma T*. Radix Astragali decoction improves liver regeneration by upregulating hepatic expression of aquaporin-9. Phytomedicine. 2024 Jan;122:155166

2.Ma Y, Zhang J, Li Y, Hu H, Ye Q, Yang C, Yang L, Zhang B*, Ma T*. Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport. Stem Cell Rev Rep. 2023 Oct;19(7):2378-2390.

3.Zhang B, Lv D, Chen Y, Nie W, Jiao Y, Zhang J, Zhou X, Wu X, Chen S, Ma T*. Aquaporin-9 facilitates liver regeneration following hepatectomy. Redox Biol. 2022 Apr;50:102246.

4.Chen X, Sun S, Huang S, Yang H, Ye Q, Lv L, Liang Y, Shan J, Xu J*, Liu W*, Ma T*. Gold(I) selenium N-heterocyclic carbene complexes as potent antibacterial agents against multidrug-resistant gram-negative bacteria via inhibiting thioredoxin reductase. Redox Biol. 2023 Apr;60:102621.

5.Zhu DD, Huang YL, Guo SY, Li N, Yang XW, Sui AR, Wu Q, Zhang Y, Kong Y, Li QF, Zhang T, Zheng WF, Li AP, Yu J*, Ma TH*, Li S*. AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Nav1.6-Mediated Astrocyte Autophagy. Adv Sci (Weinh). 2023 Mar 15:e2205862.

6.Zhu DD, Yang G, Huang YL, Zhang T, Sui AR, Li N, Su WH, Sun HL, Gao JJ, Ntim M, Guan RX, Jin LL, Yu J, Huang ZY, Ma TH*, Li S*. AQP4-A25Q Point Mutation in Mice Depolymerizes Orthogonal Arrays of Particles and Decreases Polarized Expression of AQP4 Protein in Astrocytic Endfeet at the Blood-Brain Barrier. J Neurosci. 2022 Oct 26;42(43):8169-8183.

7.Zhao F, Ma S, Zhou Y, Wei B, Hao Z, Cui X, Xing L, Liu G, Jin L, Ma T*, Shi L*. miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway. Int J Biol Sci. 2021 Oct 25;17(15):4459-4473.

8.Liu M, Liu Q, Pei Y, Gong M, Cui X, Pan J, Zhang Y, Liu Y, Liu Y, Yuan X, Zhou H, Chen Y, Sun J, Wang L, Zhang X, Wang R, Li S, Cheng J, Ding Y*, Ma T*, Yuan Y*. Aqp-1 Gene Knockout Attenuates Hypoxic Pulmonary Hypertension of Mice. Arterioscler Thromb Vasc Biol. 2019, 39:48-62.

9.Yu B, Jiang Y, Zhang B, Yang H*, Ma T*. Resveratrol dimer trans-ε-viniferin prevents rotaviral diarrhea in mice by inhibition of the intestinal calcium-activated chloride channel. Pharmacol Res. 2018 Mar;129:453-461.

10.Cui D, Sui L, Han X, Zhang M, Guo Z, Chen W, Yu X, Sun Q, Dong M, Ma T*, Kong Y*. Aquaporin-3 mediates ovarian steroid hormone-induced motility of endometrial epithelial cells. Hum Reprod. 2018 Nov 1;33(11):2060-2073.

科研项目

1.课题号82374013，国家自然科学基金面上项目，“利胆”中药黄芩靶向调控肝脏关键水通道蛋白AQP8治疗胆结石的药效物质与分子机制研究，麻彤辉，南京中医药大学，2024年1月-2027年12月，49万元。

2.课题号82073913，国家自然科学基金面上项目，肝脏星状细胞水-甘油通道AQP7调控维生素A释放在胆汁淤积性肝损伤机制中的作用，麻彤辉，南京中医药大学，2021年1月-2024年12月，55万元。

3.课题号2020YFA0509400，国家科技部重点研发计划子课题，课题-肿瘤器官选择性转移中特化外泌体的鉴定、功能及化学干预研究，南京中医药大学，2020年11月-2025年10月, 100万元。

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