朱静
教授
E-mail:830640@njucm.edu.cn
主要研究方向:
精神神经新药开发与探针晶型研究
个人简介

发明专利

1.Ahmet Hoke, Weiran Chen, Jing Zhu,Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2016.12.27, 美国,US9527817B2 (3作者共同,每人33.3%贡献)

2.Hoke Ahmet, Chen Weiran, Zhu Jing ,Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27,欧洲,EP12802536 A2 (3作者共同,每人33.3%贡献)

3.Hoke, Ahmet; Chen, Weiran; Zhu, Jing;Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27, 澳大利亚,AU2012272924 A (3作者共同,每人33.3%贡献)

4.Hoke, Ahmet; Chen, Weiran; Zhu, Jing;Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27,加拿大,CA2840003 A1 (3作者共同,每人33.3%贡献)

5.Hoke, Ahmet; Chen, Weiran; Zhu, Jing;Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27,国际,WO2012177831 A2 (3作者共同,每人33.3%贡献)

6.用于治疗周围神经病变和其它神经退行性疾病的化合物,阿梅特· 霍克, 蔚然 · 陈, 朱静,2012.12.27, 中国,CN103702669 A (3作者共同,每人33.3%贡献)

7.化疗所致周围神经病变细胞模型构建及其检测方法,朱静,肖露,薛珍珍,2017/1, 201711019268X

8.小檗碱晶体盐及其制备方法,朱静,周慧宇,索金帅,张卓珺,2018/7,201810556177x

9.一种预防和治疗化疗所致周围神经病变的中药组合物及其应用,朱静,张秋艳,杨超,2019/1,201910070648.9

10. 布洛芬小檗碱晶体盐滴丸及其制备方法,朱静,索金帅,王磊,2020/4,202010316081.1

专著

有机化学双语教材   编委   中国医药科技出版社  2020年

科研项目

1. 南京高层次人才创业项目,2019-2022100万,主持

2. 南京栖霞区高层次人才创业项目,2019-202250万,主持

3. 国家留学基金委双一流专项资助创新型人才国际合作培养项目2019-2022,  主持

4.江苏省重点研发专项社会发展面上 BE20187172018-202150万,主持

5.江苏省双创团队,500万,2018-2020,核心成员

6.江苏省六大人才高峰,2015-SWYY-0135万,2016.1-2018.12主持

7.江苏省特聘教授专项基金,神经医药学,400万,2014.11-2017.11,主持

代表性论文

1.Zhu J.#, Chen W., Mi R., Zhou C., Reed N., Höke A.*, Ethoxyquin Prevents Chemotherapy-Induced Neurotoxicity via Hsp90 Modulation.  Ann Neurol 2013, 74(6), 893-904.  

2.Meng J., Qiu S., Zhang L., You M., Xing H.and Zhu J.*, Berberine Alleviate Cisplatin-induced Peripheral Neuropathy by Modulating Inflammation Signal via TRPV1, Frontiers in Pharmacology 2022,12:774795

3.Xu R., Qiu S., Zhang J., Liu X., Zhang L., Xing H., You M., Wang M., Lu Y., Zhang P., Zhu J. *, Silibinin Schiff Base Derivatives Counteract CCl4-Induced Acute Liver Injury by Enhancing Anti-Inflammatory and Antiapoptotic Bioactivities. Drug Des Devel Ther. 2022;16:1441-1456.

4.Zhang P., Lu Y., Yang C., Zhang Q., Qian Y., Suo J., Cheng P., Zhu J. *, Based on Systematic Pharmacology: Molecular Mechanism of Siwei Jianbu Decoction in Preventing Oxaliplatin-Induced Peripheral Neuropathy, Neural Plasticity 2020, 2020(4):1-13

5. Luo Y., Zhang P., Zhang Q., Yang C., Qian Y., Suo J., Tao X., Zhu J. *, Duloxetine attenuates paclitaxel-induced peripheral nerve injury by inhibiting p53-related pathways, Journal of Pharmacology and Experimental Therapeutics 2020, 373(3):453-462 

6.Meng J.,Zhang Q., Yang C., Xiao L., Xue Z., Zhu J. *, Duloxetine, a balanced serotonin-norepinephrine reuptake inhibitor, improves painful chemotherapy-induced peripheral neuropathy by inhibiting the activation of p38 MAPK and NF-κB,Frontiers in Pharmacology 2019,10:365

7.Chen H., Zhou B., Ye R., Zhu J. *, Bao X. *, Synthesis and evaluation of a new fluorescein and rhodamine B-based chemosensor for highly sensitive and selective detection of Cysteine over other amino acids and its application in living-cell imaging, Sensors and Actuators B: Chemical 2017, 251, 481–489. 

8. Chen H., Bao X. *, Shu H., Zhou B., Ye R., Zhu J. *, Synthesis and evaluation of a novel rhodamine B-based ‘off-on’ fluorescent chemosensor for the selective determination Fe3+ ions, Sensors and Actuators B: Chemical 2016,242,921-931.

9.Wu X., Shu H., Zhou B., Geng Y., Bao X.*, Zhu J. *, Design and Synthesis of a New Rhodamine B-Based Fluorescent Probe for Selective Detection of Glutathione and Its Application for Live Cell Imaging. Sensors and Actuators B: Chemical 2016, 237, 431-442

10.Bao X.#*, Cao Q., Nie X., Zhou Y., Ye R., Zhou B., Zhu, J. *, Design and synthesis of a novel chromium(III) selective fluorescentchemosensor bearing a thiodiacetamide moiety and two rhodamine B fluorophores. Sensors and Actuators B 2015, (221) 930–939.


获得奖项与荣誉

1. 2020第三届中国医疗器械创新创业大赛优秀奖 全国 (朱静)

2. 2019 “创栖霞”大赛优胜奖  国际   (朱静)

3. 2019 转化中医药青年成果奖  全国 (朱静)             

4. 2018 免疫基础科学与转化优秀青年学者奖 全国 (朱静)

5. 2018-202江苏省双创团队 省部级 (杨晔,朱家鹏,朱静,吕志刚,顾春艳)

6. 2016-2018江苏省六大人才高峰 省部级 (朱静)

7. 2014-2017江苏省特聘教授 省部级 (朱静)

8. 2013美国优秀青年药物研究奖 国际 (朱静)

9. 2011  周围神经年会奖  国际 (朱静)

10. 2004-2008美国辛辛那提大学全额奖学金 国际 (朱静)

其他成果

发明专利

1.Ahmet Hoke, Weiran Chen, Jing Zhu,Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2016.12.27, 美国,US9527817B2 (3作者共同,每人33.3%贡献)

2.Hoke Ahmet, Chen Weiran, Zhu Jing ,Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27,欧洲,EP12802536 A2 (3作者共同,每人33.3%贡献)

3.Hoke, Ahmet; Chen, Weiran; Zhu, Jing;Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27, 澳大利亚,AU2012272924 A (3作者共同,每人33.3%贡献)

4.Hoke, Ahmet; Chen, Weiran; Zhu, Jing;Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27,加拿大,CA2840003 A1 (3作者共同,每人33.3%贡献)

5.Hoke, Ahmet; Chen, Weiran; Zhu, Jing;Compounds for treating peripheral neuropathies and other neurodegenerative disorders,2012.12.27,国际,WO2012177831 A2 (3作者共同,每人33.3%贡献)

6.用于治疗周围神经病变和其它神经退行性疾病的化合物,阿梅特· 霍克, 蔚然 · 陈, 朱静,2012.12.27, 中国,CN103702669 A (3作者共同,每人33.3%贡献)

7.化疗所致周围神经病变细胞模型构建及其检测方法,朱静,肖露,薛珍珍,2017/1, 201711019268X

8.小檗碱晶体盐及其制备方法,朱静,周慧宇,索金帅,张卓珺,2018/7,201810556177x

9.一种预防和治疗化疗所致周围神经病变的中药组合物及其应用,朱静,张秋艳,杨超,2019/1,201910070648.9

10. 布洛芬小檗碱晶体盐滴丸及其制备方法,朱静,索金帅,王磊,2020/4,202010316081.1

专著

有机化学双语教材   编委   中国医药科技出版社  2020年



南中医药学院南中医药学院学子南中医药学院研究生