程芳芳

副教授

E-mail：ffcheng@njucm.edu.cn

主要研究方向：

纳米材料在中药物质基础及药效作用机制的应用研究

个人简介

1.Yi Zhang, Da Luo, Shi-Kang Zhou, Lin Yang, Wei-Feng Yao, Fang-Fang Cheng *, Jun-Jie Zhu*, and Li Zhang*, Analytical and biomedical applications of nanomaterials in Chinese herbal medicines research,Trends in Analytical Chemistry2022, 156, 116690

2. Da Luo#, Yi Zhang#, Minyu Wang, Chen Zhu, Yue Yao, Weifeng Yao, Li Zhang*, and Fang-Fang Cheng*, Multifunctional titanium phosphate carriers for enhancing drug delivery and evaluating real-time therapeutic efficacy of a hydrophobic drug component in Euphorbia kansui, Analyst 2021, 146, 1620-1625.

3. Ji-Ming Yu, Da Luo, Zhong-Jie Ma, Bing Zheng, Fang-Fang Cheng*, and Wei-Wei Xiong*, Effective Enrichment of Low-Concentration Rare-Earth Ions by Three-Dimensional Thiostannate K2Sn2S5, ACS Applied Materials & Interfaces2021, 13, 55188-55197.

4. Da Luo, Yi Zhang, Xiaowen Yang, Fang-Fang Cheng*, and Li Zhang*, Application of up-conversion nanomaterials in detection of microRNAs, Chinese Journal of Analytical Chemistry2021, 49(9): 1428-1436.

5. Fang-Fang Cheng#, Panpan Sun#, Wei-Wei Xiong, Yi Zhang, Qiao Zhang, Weifeng Yao, Yudan Cao, and Li Zhang*, Multifunctional titanium phosphate nanoparticles for site-specific drug delivery and real-time therapeutic efficacy evaluation, Analyst2019, 144, 3103-3110.

6. Panpan Sun, Wei-Wei Xiong, Dong Zhu, Zhuhua Dong, Xuping Jin, Beibei Liu, Yi Zhang, Beihua Bao, Weifeng Yao, Li Zhang*, and Fang-Fang Cheng*, An ultrasensitive electrochemical cytosensor for highly specific detection of HL-60 cancer cells based on metal ion functionalized titanium phosphate nanospheres, Analyst 2018, 143, 5170-5175.

7. Bei-Hua Bao, Chuan-Zhu Zheng, Sheng Yu, Chen-Xiao Shan, Fang-Fang Cheng*, and Li Zhang*, Acid-induced isomerization of ticagrelor: Systematic exploration on reaction condition and mechanism, Journal of Molecular Structure2018, 1170, 38-43.

8. Fang-Fang Cheng#, Nan Jiang#, Xiaoyan Li, Li Zhang, Lihui Hu, Xiaojun Chen*, Li-Ping Jiang*, Abdel-Halim, E.S., and Jun-Jie Zhu, Target-triggered triple isothermal cascade amplification strategy for ultrasensitive microRNA-21 detection at sub-attomole level, Biosensors and Bioelectronics2016, 85, 891-896.

9. Fang-Fang Cheng, Yanjing Yang, Li Zhang*, Yudan Cao, Weifeng Yao, Yuping Tang*, and Anwei Ding, A Natural Triterpene Derivative from Euphorbia kansui Inhibits Cell Proliferation and Induces Apoptosis against Rat Intestinal Epithelioid Cell Line in Vitro, International Journal of Molecular Science 2015,16, 18956-18975.

10. Fang-Fang Cheng, Ting-Ting He, Hai-Tiao Miao, Jian-Jun Shi, Li-Ping Jiang*, and Jun-Jie Zhu*, Electron Transfer Mediated Electrochemical Biosensor for MicroRNAs Detection Based on Metal Ion Functionalized Titanium Phosphate Nanospheres at Attomole Level, ACS Applied Materials & Interfaces2015, 7, 2979-2985.

科研项目

1. 江苏省中医药管理局面上项目（MS2021005），水蛭抗肺纤维化物质基础及作用机制研究，2022/01-2024/12，主持，5万。

2. 国家自然科学基金青年项目（21705081），活体内microRNA响应的诊疗一体化纳米探针的构建与应用，2018/01-2020/12，主持，24万。

3. 江苏省自然科学基金青年项目（BK20161037），基于药物可控释放与荧光实时监测同步实现的多功能纳米载体的研究，2016/07-2019/07，主持，20万。

4. 江苏省高校自然科学研究面上项目（15KJB360009），金团簇荧光探针实时监测甘遂成分引起细胞凋亡的研究，2015/07-2017/06，主持，5万。

5. 南京大学生命分析化学国家重点实验室开放课题（SKLACLS1420），电化学生物传感器用于疾病相关miRNA的检测，2014/10-2016/12，主持，3万。

代表性论文