彭国平
教授
E-mail:guopingpeng@sohu.com
主要研究方向:
中药化学成分、中药提取精制及制剂研究
个人简介

1.Cunyu Li, Chenguang Zhao, Yun Ma, Wei Chen, Yunfeng Zheng, Xinglei Zhi*, Guoping Peng*. Optimization of ultrasonic-assisted ultrafiltration process for removing bacterial endotoxin from diammonium glycyrrhizinate using response surface methodology [J]. Ultrasonics – Sonochemistry, 2020, 68: 105215.

2.Cunyu Li, Yun Ma, Li Ma, Xinglei Zhi, Guoping Peng*. Improving the clarity and sensitization of polysorbate 80 by ultrasonic-assisted ultrafiltration technology [J]. European Journal of Pharmaceutical Sciences, 2021, 159: 105719.

3.Fang Wang, Cunyu Li, Yunfeng Zheng,Hongyang Li, Wei Xiao, Guoping Peng*.  Identification of the allergenic ingredients in Reduning injection by ultrafiltration and high-performance liquid chromatography. Journal of Immunology Research, 2016, 2016(2):1-7.

4.Fang Wang, Zebin Weng, Cunyu Li, Guoping Peng*. A reliable method for the evaluation of the anaphylactoid reaction caused by injectable drugs. Molecules, 2016, 21(10):1352.

5.Fang Wang, Huanhuan Zhong, Weike Chen, Qingpu Liu, Cunyu Li, Yunfeng Zheng, Guoping Peng*. Potential hypoglycaemic activity phenolic glycosides from Moringa oleifera seeds[J]. Natural Product Research, 2017, 31(16): 1869-1874.

6.Tingting Liang, Shun Liu, Fang Wang, Jiamei Gu, Yang Lv, Weike Chen, Cunyu Li, Yunfeng Zheng, Guoping Peng*. A UPLC-MS/MS method for simultaneous determination of 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin in rat plasma and its application in pharmacokinetic and absolute bioavailability studies. Journal of Chromatography B, 2018:205-210.

7.Weike Chen, Tingting Liang, Wenwen ZuoXin Wu, , Guoping Peng*. Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, β-amyloid deposition, and neuroinflammation in the SAMP8 mice. Biomedicine & pharmacotherapy, 2018, 106:92-97.

8.Fang Wang, Huanhuan Zhong,Shiqi Fang, Yunfeng Zheng, Cunyu Li, Guoping Peng*, Xinchun Shen. Potential anti-inflammatory sesquiterpene lactones from Eupatorium lindleyanum[J]. Planta Medica, 2017:123-128.

9.Guoping Peng*, Gang Tian, Xianfeng Huang. Guaiane-type sesquiterpenoids from Alisma orientalis. Phytochemistry, 2003, 63(8):877-881.

10.Guoping Peng*, Fengchang Lou, Xianfeng Huang. Structure of orientanone from Alisma orientalis, a novel sesquiterpene originating from guaiane-type carbon skeleton by isopropyl shift. Tetrahedron, 2002, 58(44):9045-9048.

科研项目

1.国家自然科学基金面上项目(82074006),中药注射剂过敏性休克(风暴)的类过敏叠加反应机制与质量控制,2021/01-2024/12,主持,55万元

2.国家自然科学基金面上项目(81373980),基于界面狭孔效应的中药成分超滤分离规律研究,2014/01-2017/12,主持,70万元

3.国家中药标准化项目(ZYBZH-C-JS-34),新生化颗粒标准化建设,2016/01-2018/12,主持,120万元

4.横向开发项目(2020-WTYJ001),中药创新药IHa原料及片剂药学研究,2020/07-2024/12,主持,450万元

5.横向开发项目,经典名方“当归补血汤”颗粒剂研发,2018/08-2023/7,主持,110万元

代表性论文

1.Cunyu Li, Chenguang Zhao, Yun Ma, Wei Chen, Yunfeng Zheng, Xinglei Zhi*, Guoping Peng*. Optimization of ultrasonic-assisted ultrafiltration process for removing bacterial endotoxin from diammonium glycyrrhizinate using response surface methodology [J]. Ultrasonics – Sonochemistry, 2020, 68: 105215.

2.Cunyu Li, Yun Ma, Li Ma, Xinglei Zhi, Guoping Peng*. Improving the clarity and sensitization of polysorbate 80 by ultrasonic-assisted ultrafiltration technology [J]. European Journal of Pharmaceutical Sciences, 2021, 159: 105719.

3.Fang Wang, Cunyu Li, Yunfeng Zheng,Hongyang Li, Wei Xiao, Guoping Peng*.  Identification of the allergenic ingredients in Reduning injection by ultrafiltration and high-performance liquid chromatography. Journal of Immunology Research, 2016, 2016(2):1-7.

4.Fang Wang, Zebin Weng, Cunyu Li, Guoping Peng*. A reliable method for the evaluation of the anaphylactoid reaction caused by injectable drugs. Molecules, 2016, 21(10):1352.

5.Fang Wang, Huanhuan Zhong, Weike Chen, Qingpu Liu, Cunyu Li, Yunfeng Zheng, Guoping Peng*. Potential hypoglycaemic activity phenolic glycosides from Moringa oleifera seeds[J]. Natural Product Research, 2017, 31(16): 1869-1874.

6.Tingting Liang, Shun Liu, Fang Wang, Jiamei Gu, Yang Lv, Weike Chen, Cunyu Li, Yunfeng Zheng, Guoping Peng*. A UPLC-MS/MS method for simultaneous determination of 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin in rat plasma and its application in pharmacokinetic and absolute bioavailability studies. Journal of Chromatography B, 2018:205-210.

7.Weike Chen, Tingting Liang, Wenwen ZuoXin Wu, , Guoping Peng*. Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, β-amyloid deposition, and neuroinflammation in the SAMP8 mice. Biomedicine & pharmacotherapy, 2018, 106:92-97.

8.Fang Wang, Huanhuan Zhong,Shiqi Fang, Yunfeng Zheng, Cunyu Li, Guoping Peng*, Xinchun Shen. Potential anti-inflammatory sesquiterpene lactones from Eupatorium lindleyanum[J]. Planta Medica, 2017:123-128.

9.Guoping Peng*, Gang Tian, Xianfeng Huang. Guaiane-type sesquiterpenoids from Alisma orientalis. Phytochemistry, 2003, 63(8):877-881.

10.Guoping Peng*, Fengchang Lou, Xianfeng Huang. Structure of orientanone from Alisma orientalis, a novel sesquiterpene originating from guaiane-type carbon skeleton by isopropyl shift. Tetrahedron, 2002, 58(44):9045-9048.

获得奖项与荣誉

1.《中药资源化学研究体系建立及其在生产与利用中的应用》,国家科学技术进步二等奖(排13),2011年

2.《中药资源及资源化学基础与应用示范性研究》,教育部科学技术进步一等奖(排13),2009年

3.《泽泻标准物质及标准化用药的研究》, 江苏省科技进步三等奖(排1),1999年

4.《膜分离技术与吸附树脂联用精制中药的研究》, 江苏省科技进步三等奖(排3),2002年

5.《针箭颗粒治疗高血压病胰岛素抵抗的临床与实验研究》, 江苏省科技进步三等奖(排3),2003年

6.第十二届“挑战杯”大学生课外学术科技作品特等奖《注射剂中热原专用超滤膜及在线检测仪》,指导老师,2011年

7.第八届“挑战杯”中国大学生创业计划竞赛金奖《天泽医药科技有限公司》,指导老师,2012年

其他成果

专利

1.彭国平, 李存玉, 支兴蕾, 段金廒, 郑云枫, 李红阳. 一种超滤膜截留分子量的测定方法, 中国, 201410116363.1

2.彭国平, 李红阳, 郑云枫. 纳米粒子辨识系统装置及其识别方法, 中国, 2012101965686

3.彭国平, 李红阳, 郑云枫. 纳米粒径分析仪用于内毒素检测的方法, 中国, 2012101966566

教材

彭国平. 中药制药化学.中国中医药出版社,2016年2月



南中医药学院南中医药学院学子南中医药学院研究生