[1] Yi Shuang Wang^#, Bo Zhang^#, Jiapeng Zhu, Cheng Long Yang, Yu Guo, Cheng Li Liu, Fang Liu, Huiqin Huang, Suwen Zhao, Yong Liang, Rui Hua Jiao, Ren Xiang Tan*, Hui Ming Ge*. Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis. J. Am. Chem. Soc. 2018, 140, 10909‒10914.

[2] Fao Wen Jiao^#, Yi Shuang Wang^#, Xue Ting You, Wan Qing Wei, Yu Chen, Cheng Long Yang Zhi Kai Guo, Bo Zhang, Yong Liang*, Ren Xiang Tan*, Rui Hua Jiao*, Hui Ming Ge*. An NADPH-Dependent Ketoreductase Catalyses the Tetracyclic to Pentacyclic Skeletal Rearrangement in Chartreusin Biosynthesis, Angew. Chem. Int. Ed. Engl. 2021, 60, 26378-26384.

[3] Yi Shuang Wang^#, Wan Zheng^#, Nan Jiang^#, Yun Xia Jin^#, Zi Kang Meng, Meng Xin Sun, Yu Liang Zong, Tong Xu, Jia Peng Zhu*, Ren Xiang Tan*. Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution. Angew. Chem. Int. Ed. Engl. 2022, e202201321. 

[4] Cheng Long Yang, Yi Shuang Wang, Cheng Li Liu, Ying Jie Zeng, Ping Cheng, Rui Hua Jiao, Shi Xiang Bao, Hui Qin Huang, Ren Xiang Tan*, Hui Ming Ge*. Strepchazolins A and B: Two New Alkaloids from a Marine Streptomyces chartreusis NA02069. Mar. Drugs 2017, 15, 244‒251.

[5] Mei Zhang , Cheng Long Yang, Yong Sheng Xiao, Bo Zhang, Zi Xin Deng, Li Yang, Jing Shi, Yi Shuang Wang, Wei Li, Rui Hua Jiao, Ren Xiang Tan*, Hui Ming Ge*. Aurachin SS, a new antibiotic from Streptomyces sp. NA04227. J. Antibiot. 2017, 70, 853-855.

1.国家自然科学基金委员会, 青年科学基金项目, 82003608, 新骨架聚酮生物碱chartazones的生物合成 研究, 2021-01-01 至 2023-12-31, 24万元, 主持。 

2.国家自然科学基金委员会, 面上项目, 82073721, 基于仿生组合化学－(聚酮)吲哚生物碱的真菌合成 与Aurora B抑制研究, 2021-01-01 至 2024-12-31, 55万元,  参与。 

3.国家自然科学基金委员会, 重大项目, 81991524, 海洋药源分子的形成机制与调控策略, 2020-01-01 至 2024-12-31, 400万元, 参与。

4.国家自然科学基金委员会, 面上项目, 81773591, 新型beta-内酯化合物strepenlactone的生物合成研 究, 2018-01-01 至 2021-12-31, 54万元, 参与。 

5.国家自然科学基金委员会, 面上项目, 81673333, 新型抗厌氧菌生物碱化合物的生物合成与作用机制研究, 2017-01-01 至 2020-12-31, 50万元, 参与。

[1] Yi Shuang Wang^#, Bo Zhang^#, Jiapeng Zhu, Cheng Long Yang, Yu Guo, Cheng Li Liu, Fang Liu, Huiqin Huang, Suwen Zhao, Yong Liang, Rui Hua Jiao, Ren Xiang Tan*, Hui Ming Ge*. Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis. J. Am. Chem. Soc. 2018, 140, 10909‒10914.

[2] Fao Wen Jiao^#, Yi Shuang Wang^#, Xue Ting You, Wan Qing Wei, Yu Chen, Cheng Long Yang Zhi Kai Guo, Bo Zhang, Yong Liang*, Ren Xiang Tan*, Rui Hua Jiao*, Hui Ming Ge*. An NADPH-Dependent Ketoreductase Catalyses the Tetracyclic to Pentacyclic Skeletal Rearrangement in Chartreusin Biosynthesis, Angew. Chem. Int. Ed. Engl. 2021, 60, 26378-26384.

[3] Yi Shuang Wang^#, Wan Zheng^#, Nan Jiang^#, Yun Xia Jin^#, Zi Kang Meng, Meng Xin Sun, Yu Liang Zong, Tong Xu, Jia Peng Zhu*, Ren Xiang Tan*. Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution. Angew. Chem. Int. Ed. Engl. 2022, e202201321. 

[4] Cheng Long Yang, Yi Shuang Wang, Cheng Li Liu, Ying Jie Zeng, Ping Cheng, Rui Hua Jiao, Shi Xiang Bao, Hui Qin Huang, Ren Xiang Tan*, Hui Ming Ge*. Strepchazolins A and B: Two New Alkaloids from a Marine Streptomyces chartreusis NA02069. Mar. Drugs 2017, 15, 244‒251.

[5] Mei Zhang , Cheng Long Yang, Yong Sheng Xiao, Bo Zhang, Zi Xin Deng, Li Yang, Jing Shi, Yi Shuang Wang, Wei Li, Rui Hua Jiao, Ren Xiang Tan*, Hui Ming Ge*. Aurachin SS, a new antibiotic from Streptomyces sp. NA04227. J. Antibiot. 2017, 70, 853-855.